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Photoredox-catalyzed Site-selective α-C(sp(3))-H Alkylation of Primary Amine Derivatives

The synthetic utility of tertiary amines to oxidatively generate α-amino radicals is well established; however, primary amines remain challenging due to competitive side reactions. This report describes the site-selective α-functionalization of primary amine derivatives through the generation of α-a...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Ashley, Melissa A., Yamauchi, Chiaki, Chu, John C. K., Otsuka, Shinya, Yorimitsu, Hideki, Rovis, Tomislav
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442930/
https://ncbi.nlm.nih.gov/pubmed/30768740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201812227
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