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Epigenomic promoter alterations predict for benefit from immune checkpoint inhibition in metastatic gastric cancer
BACKGROUND: Utilization of alternative transcription start sites through alterations in epigenetic promoter regions causes reduced expression of immunogenic N-terminal peptides, which may facilitate immune evasion in early gastric cancer. We hypothesized that tumors with high alternate promoter util...
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| Publicado no: | Ann Oncol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442650/ https://ncbi.nlm.nih.gov/pubmed/30624548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy550 |
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