Biphasic mechanosensitivity of T cell receptor-mediated spreading of lymphocytes

Mechanosensing by T cells through the T cell receptor (TCR) is at the heart of immune recognition. While the mechanobiology of the TCR at the molecular level is increasingly well documented, its link to cell-scale response is poorly understood. Here we explore T cell spreading response as a function...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wahl, Astrid, Dinet, Céline, Dillard, Pierre, Nassereddine, Aya, Puech, Pierre-Henri, Limozin, Laurent, Sengupta, Kheya
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442626/
https://ncbi.nlm.nih.gov/pubmed/30850545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811516116
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