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Tuning the Formation and Rupture of Single Ligand-Receptor Bonds by Hyaluronan-Induced Repulsion

We used a combination of laminar flow chamber and reflection interference microscopy to study the formation and rupture of single bonds formed between Fc-ICAM-1 attached to a substrate and anti-ICAM-1 carried by micrometric beads in the presence of a repulsive hyaluronan (HA) layer adsorbed onto the...

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Autors principals: Robert, Philippe, Sengupta, Kheya, Puech, Pierre-Henri, Bongrand, Pierre, Limozin, Laurent
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553109/
https://ncbi.nlm.nih.gov/pubmed/18599637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.135947
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