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A Rough Energy Landscape to Describe Surface-Linked Antibody and Antigen Bond Formation

Antibodies and B cell receptors often bind their antigen at cell-cell interface while both molecular species are surface-bound, which impacts bond kinetics and function. Despite the description of complex energy landscapes for dissociation kinetics which may also result in significantly different as...

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Pubblicato in:Sci Rep
Autori principali: Limozin, Laurent, Bongrand, Pierre, Robert, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059681/
https://ncbi.nlm.nih.gov/pubmed/27731375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35193
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