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T Cells on Engineered Substrates: The Impact of TCR Clustering Is Enhanced by LFA-1 Engagement
We created APC-mimetic synthetic substrates to study the impact of ligand clustering on T cell activation and spreading. The substrates exhibit antibodies directed against the TCR-complex in the form of a patterned array of sub micrometric dots surrounded by a fluid supported lipid bilayer (SLB) whi...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6154019/ https://ncbi.nlm.nih.gov/pubmed/30279692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02085 |
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