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Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior
Previous studies have shown that insulin and IGF-1 signaling in the brain, especially the hypothalamus, is important for regulation of systemic metabolism. Here, we develop mice in which we have specifically inactivated both insulin receptors (IRs) and IGF-1 receptors (IGF1Rs) in the hippocampus (Hi...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442573/ https://ncbi.nlm.nih.gov/pubmed/30765523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817391116 |
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