Učitavanje...
Identification of human silencers by correlating cross-tissue epigenetic profiles and gene expression
Compared to enhancers, silencers are notably difficult to identify and validate experimentally. In search for human silencers, we utilized H3K27me3-DNase I hypersensitive site (DHS) peaks with tissue specificity negatively correlated with the expression of nearby genes across 25 diverse cell lines....
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| Izdano u: | Genome Res |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442386/ https://ncbi.nlm.nih.gov/pubmed/30886051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.247007.118 |
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