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Epigenetic and genetic alterations and their influence on gene regulation in chronic lymphocytic leukemia
BACKGROUND: To understand the changes of gene regulation in carcinogenesis, we explored signals of DNA methylation – a stable epigenetic mark of gene regulatory elements — and designed a computational model to profile loss and gain of regulatory elements (REs) during carcinogenesis. We also utilized...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5353786/ https://ncbi.nlm.nih.gov/pubmed/28302063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3617-6 |
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