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CG dinucleotides enhance promoter activity independent of DNA methylation
Most mammalian RNA polymerase II initiation events occur at CpG islands, which are rich in CpGs and devoid of DNA methylation. Despite their relevance for gene regulation, it is unknown to what extent the CpG dinucleotide itself actually contributes to promoter activity. To address this question, we...
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| Publicado en: | Genome Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442381/ https://ncbi.nlm.nih.gov/pubmed/30709850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.241653.118 |
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