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Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias

Deposition of variant histones provides a mechanism to reset and to potentially specify chromatin states. We determined the distribution of H3 and its variant H3.3 relative to chromatin structure and elongating polymerase. H3.3 is enriched throughout active genes similar to polymerase, yet its distr...

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Bibliografske podrobnosti
Main Authors: Wirbelauer, Christiane, Bell, Oliver, Schübeler, Dirk
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182337/
https://ncbi.nlm.nih.gov/pubmed/16077006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.347705
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