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Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias

Deposition of variant histones provides a mechanism to reset and to potentially specify chromatin states. We determined the distribution of H3 and its variant H3.3 relative to chromatin structure and elongating polymerase. H3.3 is enriched throughout active genes similar to polymerase, yet its distr...

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Hlavní autoři: Wirbelauer, Christiane, Bell, Oliver, Schübeler, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182337/
https://ncbi.nlm.nih.gov/pubmed/16077006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.347705
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