Engineering a murine cell line for the stable propagation of hamster prions

Prions are infectious protein aggregates that cause several fatal neurodegenerative diseases. Prion research has been hindered by a lack of cellular paradigms for studying the replication of prions from different species. Although hamster prions have been widely used to study prion replication in an...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bourkas, Matthew E. C., Arshad, Hamza, Al-Azzawi, Zaid A. M., Halgas, Ondrej, Shikiya, Ronald A., Mehrabian, Mohadeseh, Schmitt-Ulms, Gerold, Bartz, Jason C., Watts, Joel C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442044/
https://ncbi.nlm.nih.gov/pubmed/30705093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007135
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