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Engineering a murine cell line for the stable propagation of hamster prions

Prions are infectious protein aggregates that cause several fatal neurodegenerative diseases. Prion research has been hindered by a lack of cellular paradigms for studying the replication of prions from different species. Although hamster prions have been widely used to study prion replication in an...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Bourkas, Matthew E. C., Arshad, Hamza, Al-Azzawi, Zaid A. M., Halgas, Ondrej, Shikiya, Ronald A., Mehrabian, Mohadeseh, Schmitt-Ulms, Gerold, Bartz, Jason C., Watts, Joel C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442044/
https://ncbi.nlm.nih.gov/pubmed/30705093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007135
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