Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy

Mitochondrial dysfunction has been implicated in a wide variety of degenerative diseases, including age-related macular degeneration. Damage to mitochondria and mitochondrial DNA accumulates with age in the postmitotic retinal pigment epithelium (RPE), which could lead to RPE cell death and trigger...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oxid Med Cell Longev
Päätekijät: Hytti, Maria, Korhonen, Eveliina, Hyttinen, Juha M. T., Roehrich, Heidi, Kaarniranta, Kai, Ferrington, Deborah A., Kauppinen, Anu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441541/
https://ncbi.nlm.nih.gov/pubmed/31007832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1583656
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