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Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process

The NF-κB signaling system and the autophagic degradation pathway are crucial cellular survival mechanisms, both being well conserved during evolution. Emerging studies have indicated that the IKK/NF-κB signaling axis regulates autophagy in a context-dependent manner. IKK complex and NF-κB can enhan...

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Detalhes bibliográficos
Main Authors: Salminen, Antero, Hyttinen, Juha M. T., Kauppinen, Anu, Kaarniranta, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412117/
https://ncbi.nlm.nih.gov/pubmed/22899934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/849541
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