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Differentially mutated subnetworks discovery

PROBLEM: We study the problem of identifying differentially mutated subnetworks of a large gene–gene interaction network, that is, subnetworks that display a significant difference in mutation frequency in two sets of cancer samples. We formally define the associated computational problem and show t...

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Detalhes bibliográficos
Publicado no:Algorithms Mol Biol
Main Authors: Hajkarim, Morteza Chalabi, Upfal, Eli, Vandin, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441493/
https://ncbi.nlm.nih.gov/pubmed/30976291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-019-0146-7
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