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Differentially mutated subnetworks discovery

PROBLEM: We study the problem of identifying differentially mutated subnetworks of a large gene–gene interaction network, that is, subnetworks that display a significant difference in mutation frequency in two sets of cancer samples. We formally define the associated computational problem and show t...

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Vydáno v:Algorithms Mol Biol
Hlavní autoři: Hajkarim, Morteza Chalabi, Upfal, Eli, Vandin, Fabio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441493/
https://ncbi.nlm.nih.gov/pubmed/30976291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-019-0146-7
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