Structure mapping of dengue and Zika viruses reveals functional long-range interactions

Dengue (DENV) and Zika (ZIKV) viruses are clinically important members of the Flaviviridae family with an 11 kb positive strand RNA genome that folds to enable virus function. Here, we perform structure and interaction mapping on four DENV and ZIKV strains inside virions and in infected cells. Compa...

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Publicado no:Nat Commun
Main Authors: Huber, Roland G., Lim, Xin Ni, Ng, Wy Ching, Sim, Adelene Y. L., Poh, Hui Xian, Shen, Yang, Lim, Su Ying, Sundstrom, Karin B., Sun, Xuyang, Aw, Jong Ghut, Too, Horng Khit, Boey, Peng Hee, Wilm, Andreas, Chawla, Tanu, Choy, Milly M., Jiang, Lu, de Sessions, Paola Florez, Loh, Xian Jun, Alonso, Sylvie, Hibberd, Martin, Nagarajan, Niranjan, Ooi, Eng Eong, Bond, Peter J., Sessions, October M., Wan, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441010/
https://ncbi.nlm.nih.gov/pubmed/30926818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09391-8
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