PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

B-cell lymphoma (BCL) is the most common hematologic malignancy. While sequencing studies gave insights into BCL genetics, identification of non-mutated cancer genes remains challenging. Here, we describe PiggyBac transposon tools and mouse models for recessive screening and show their application t...

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Publicado no:Nat Commun
Main Authors: Weber, Julia, de la Rosa, Jorge, Grove, Carolyn S., Schick, Markus, Rad, Lena, Baranov, Olga, Strong, Alexander, Pfaus, Anja, Friedrich, Mathias J., Engleitner, Thomas, Lersch, Robert, Öllinger, Rupert, Grau, Michael, Menendez, Irene Gonzalez, Martella, Manuela, Kohlhofer, Ursula, Banerjee, Ruby, Turchaninova, Maria A., Scherger, Anna, Hoffman, Gary J., Hess, Julia, Kuhn, Laura B., Ammon, Tim, Kim, Johnny, Schneider, Günter, Unger, Kristian, Zimber-Strobl, Ursula, Heikenwälder, Mathias, Schmidt-Supprian, Marc, Yang, Fengtang, Saur, Dieter, Liu, Pentao, Steiger, Katja, Chudakov, Dmitriy M., Lenz, Georg, Quintanilla-Martinez, Leticia, Keller, Ulrich, Vassiliou, George S., Cadiñanos, Juan, Bradley, Allan, Rad, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440946/
https://ncbi.nlm.nih.gov/pubmed/30926791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09180-3
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