Mapping tissue pH in an experimental model of acute stroke – Determination of graded regional tissue pH changes with non-invasive quantitative amide proton transfer MRI

pH-weighted amide proton transfer (APT) MRI is sensitive to tissue pH change during acute ischemia, complementing conventional perfusion and diffusion stroke imaging. However, the currently used pH-weighted magnetization transfer (MT) ratio asymmetry (MTR(asym)) analysis is of limited pH specificity...

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Wang, Enfeng, Wu, Yin, Cheung, Jerry S, Igarashi, Takahiro, Wu, Limin, Zhang, Xiaoan, Sun, Phillip Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440806/
https://ncbi.nlm.nih.gov/pubmed/30753926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2019.02.022
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