pH-sensitive MRI demarcates graded tissue acidification during acute stroke — pH specificity enhancement with magnetization transfer and relaxation-normalized amide proton transfer (APT) MRI

pH-sensitive amide proton transfer (APT) MRI provides a surrogate metabolic biomarker that complements the widely-used perfusion and diffusion imaging. However, the endogenous APT MRI is often calculated using the asymmetry analysis (MTR(asym)), which is susceptible to an inhomogeneous shift due to...

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Publicado no:Neuroimage
Main Authors: Guo, Yingkun, Zhou, Iris Yuwen, Chan, Suk-Tak, Wang, Yu, Mandeville, Emiri T., Igarashi, Takahiro, Lo, Eng H., Ji, Xunming, Sun, Phillip Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026952/
https://ncbi.nlm.nih.gov/pubmed/27444569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2016.07.025
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