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Imaging acute ischemic tissue acidosis with pH-sensitive endogenous amide proton transfer (APT) MRI - Correction of tissue relaxation and concomitant RF irradiation effects toward mapping quantitative cerebral tissue pH

Amide proton transfer (APT) MRI is sensitive to ischemic tissue acidosis and has been increasingly used as a research tool to investigate disrupted tissue metabolism during acute stroke. However, magnetization transfer asymmetry (MTR(asym)) analysis is often used for calculating APT contrast, which...

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Opis bibliograficzny
Główni autorzy: Sun, Phillip Zhe, Wang, Enfeng, Cheung, Jerry S
Format: Artigo
Język:Inglês
Wydane: 2011
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288866/
https://ncbi.nlm.nih.gov/pubmed/22178815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2011.11.091
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