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Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization
Metastasis-initiating cells dynamically adapt to the distinct microenvironments of different organs, but these early adaptations are poorly understood due to the limited sensitivity of in situ transcriptomics. We developed fluorouracil-labeled RNA sequencing (Flura-seq) for in situ analysis with hig...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6440742/ https://ncbi.nlm.nih.gov/pubmed/30912515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43627 |
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