Pericyte-Like Spreading by Disseminated Cancer Cells Activates YAP and MRTF for Metastatic Colonization

Metastatic seeding by disseminated cancer cells principally occurs in perivascular niches. Here, we show that mechanotransduction signaling triggered by the pericyte-like spreading of disseminated cancer cells on host tissue capillaries is critical for metastatic colonization. Disseminated cancer ce...

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Bibliografske podrobnosti
izdano v:Nat Cell Biol
Main Authors: Er, Ekrem Emrah, Valiente, Manuel, Ganesh, Karuna, Zou, Yilong, Agrawal, Saloni, Hu, Jing, Griscom, Bailey, Rosenblum, Marc, Boire, Adrienne, Brogi, Edi, Giancotti, Filippo, Schachner, Melitta, Malladi, Srinivas, Massagué, Joan
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467203/
https://ncbi.nlm.nih.gov/pubmed/30038252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0138-8
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