Pericyte-Like Spreading by Disseminated Cancer Cells Activates YAP and MRTF for Metastatic Colonization

Metastatic seeding by disseminated cancer cells principally occurs in perivascular niches. Here, we show that mechanotransduction signaling triggered by the pericyte-like spreading of disseminated cancer cells on host tissue capillaries is critical for metastatic colonization. Disseminated cancer ce...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Er, Ekrem Emrah, Valiente, Manuel, Ganesh, Karuna, Zou, Yilong, Agrawal, Saloni, Hu, Jing, Griscom, Bailey, Rosenblum, Marc, Boire, Adrienne, Brogi, Edi, Giancotti, Filippo, Schachner, Melitta, Malladi, Srinivas, Massagué, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467203/
https://ncbi.nlm.nih.gov/pubmed/30038252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0138-8
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