One-step mechanochemical preparation and prominent antitumor activity of SN-38 self-micelle solid dispersion

PURPOSE: The purpose of this study was to overcome the clinical defects of 7-ethyl-10-hydroxycamptothecin (SN-38) and explore its characteristics and antitumor effects. MATERIALS AND METHODS: An amorphous solid dispersion of SN-38 with disodium glycyrrhizin (Na(2)GA) was prepared by mechanical ball...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Autores principales: Sun, Xuanrong, Zhu, Dabu, Cai, Yue, Shi, Guobang, Gao, Mengshi, Zheng, Minzi
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2019
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440449/
https://ncbi.nlm.nih.gov/pubmed/30988612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S193783
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