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Dissolution Properties and Physical Characterization of Telmisartan–Chitosan Solid Dispersions Prepared by Mechanochemical Activation

Solid dispersion systems of telmisartan (a poorly water-soluble antihypertension drug) with biopolymer carrier chitosan have been investigated in this study. The mechanism of solubilization of chitosan for drug has been studied. In addition, the influence of several factors was carefully examined, i...

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Detalhes bibliográficos
Main Authors: Zhong, Lin, Zhu, Xingyi, Luo, Xiaofang, Su, Weike
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665993/
https://ncbi.nlm.nih.gov/pubmed/23430728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9937-1
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