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A new class of constitutively active super-enhancers is associated with fast recovery of 3D chromatin loops

BACKGROUND: Super-enhancers or stretch enhancers are clusters of active enhancers that often coordinate cell-type specific gene regulation during development and differentiation. In addition, the enrichment of disease-associated single nucleotide polymorphism in super-enhancers indicates their criti...

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Publicat a:BMC Bioinformatics
Autors principals: Ryu, Jayoung, Kim, Hyunwoong, Yang, Dongchan, Lee, Andrew J., Jung, Inkyung
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439976/
https://ncbi.nlm.nih.gov/pubmed/30925856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2646-3
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