Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

BACKGROUND: Mitochondrial disease is a family of genetic disorders characterized by defects in the generation and regulation of energy. Epilepsy is a common symptom of mitochondrial disease, and in the vast majority of cases, refractory to commonly used antiepileptic drugs. Ferroptosis is a recently...

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Opis bibliograficzny
Wydane w:PLoS One
Główni autorzy: Kahn-Kirby, Amanda H., Amagata, Akiko, Maeder, Celine I., Mei, Janet J., Sideris, Steve, Kosaka, Yuko, Hinman, Andrew, Malone, Stephanie A., Bruegger, Joel J., Wang, Leslie, Kim, Virna, Shrader, William D., Hoff, Kevin G., Latham, Joey C., Ashley, Euan A., Wheeler, Matthew T., Bertini, Enrico, Carrozzo, Rosalba, Martinelli, Diego, Dionisi-Vici, Carlo, Chapman, Kimberly A., Enns, Gregory M., Gahl, William, Wolfe, Lynne, Saneto, Russell P., Johnson, Simon C., Trimmer, Jeffrey K., Klein, Matthew B., Holst, Charles R.
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2019
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438538/
https://ncbi.nlm.nih.gov/pubmed/30921410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214250
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