Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

BACKGROUND: Mitochondrial disease is a family of genetic disorders characterized by defects in the generation and regulation of energy. Epilepsy is a common symptom of mitochondrial disease, and in the vast majority of cases, refractory to commonly used antiepileptic drugs. Ferroptosis is a recently...

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發表在:PLoS One
Main Authors: Kahn-Kirby, Amanda H., Amagata, Akiko, Maeder, Celine I., Mei, Janet J., Sideris, Steve, Kosaka, Yuko, Hinman, Andrew, Malone, Stephanie A., Bruegger, Joel J., Wang, Leslie, Kim, Virna, Shrader, William D., Hoff, Kevin G., Latham, Joey C., Ashley, Euan A., Wheeler, Matthew T., Bertini, Enrico, Carrozzo, Rosalba, Martinelli, Diego, Dionisi-Vici, Carlo, Chapman, Kimberly A., Enns, Gregory M., Gahl, William, Wolfe, Lynne, Saneto, Russell P., Johnson, Simon C., Trimmer, Jeffrey K., Klein, Matthew B., Holst, Charles R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438538/
https://ncbi.nlm.nih.gov/pubmed/30921410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214250
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