Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

BACKGROUND: Mitochondrial disease is a family of genetic disorders characterized by defects in the generation and regulation of energy. Epilepsy is a common symptom of mitochondrial disease, and in the vast majority of cases, refractory to commonly used antiepileptic drugs. Ferroptosis is a recently...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kahn-Kirby, Amanda H., Amagata, Akiko, Maeder, Celine I., Mei, Janet J., Sideris, Steve, Kosaka, Yuko, Hinman, Andrew, Malone, Stephanie A., Bruegger, Joel J., Wang, Leslie, Kim, Virna, Shrader, William D., Hoff, Kevin G., Latham, Joey C., Ashley, Euan A., Wheeler, Matthew T., Bertini, Enrico, Carrozzo, Rosalba, Martinelli, Diego, Dionisi-Vici, Carlo, Chapman, Kimberly A., Enns, Gregory M., Gahl, William, Wolfe, Lynne, Saneto, Russell P., Johnson, Simon C., Trimmer, Jeffrey K., Klein, Matthew B., Holst, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438538/
https://ncbi.nlm.nih.gov/pubmed/30921410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214250
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