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Readers of DNA methylation, the MBD family as potential therapeutic targets
DNA methylation represents a fundamental epigenetic modification that regulates chromatin architecture and gene transcription. Many diseases, including cancer, show aberrant methylation patterns that contribute to the disease phenotype. DNA methylation inhibitors have been used to block methylation...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6438182/ https://ncbi.nlm.nih.gov/pubmed/29128342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.11.002 |
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