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Diet-Induced Insulin Resistance Elevates Hippocampal Glutamate as well as VGLUT1 and GFAP Expression in AβPP/PS1 Mice

The symptomologies of Alzheimer’s disease (AD) develop over decades suggesting modifiable life-style factors may contribute to disease pathogenesis. In humans, hyperinsulinemia associated with type 2 diabetes mellitus increases the risk for developing AD and both diseases share similar age-related e...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Hascup, Erin R., Broderick, Sarah O., Russell, Mary K., Fang, Yimin, Bartke, Andrzej, Boger, Heather A., Hascup, Kevin N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438176/
https://ncbi.nlm.nih.gov/pubmed/30472734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14634
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