VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses

Glutamate is the major excitatory transmitter in the vertebrate nervous system. To maintain synaptic efficacy, recycling synaptic vesicles (SV) are refilled with glutamate by vesicular glutamate transporters (VGLUTs). The dynamics and mechanism of glutamate uptake in intact neurons are still largely...

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Udgivet i:Nat Commun
Main Authors: Martineau, Magalie, Guzman, Raul E., Fahlke, Christoph, Klingauf, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741633/
https://ncbi.nlm.nih.gov/pubmed/29273736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02367-6
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