Natural Killer Cell Degranulation Defect: A Cause for Impaired NK-Cell Cytotoxicity and Hyperinflammation in Fanconi Anemia Patients

Fanconi anemia (FA) is a rare inherited syndrome characterized by progressive bone marrow failure (BMF), abnormal skin pigmentation, short stature, and increased cancer risk. BMF in FA is multifactorial and largely results from the death of hematopoietic stem cells due to genomic instability. Also,...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Shabrish, Snehal, Kelkar, Madhura, Chavan, Niranjan, Desai, Mukesh, Bargir, Umair, Gupta, Maya, Mehta, Priti, Chichra, Akanksha, S, Chandrakala, Taur, Prasad, Saxena, Vinay, Vundinti, Babu Rao, Madkaikar, Manisha
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
Immunology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438155/
https://ncbi.nlm.nih.gov/pubmed/30949167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00490
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