LncRNA BCAR4, targeting to miR-665/STAT3 signaling, maintains cancer stem cells stemness and promotes tumorigenicity in colorectal cancer

BACKGROUND: Breast cancer anti-estrogen resistance 4 (BCAR4) is closely associated with colorectal cancer (CRC) initiation and propagation. However, the mechanisms underlying BCAR4 function in colon cancer remains largely unknown. In this study, we hypothesized that BCAR4 could regulate colon cancer...

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Publicat a:Cancer Cell Int
Autors principals: Ouyang, Shurui, Zhou, Xin, Chen, Zhengquan, Wang, Maijian, Zheng, Xinbin, Xie, Ming
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438025/
https://ncbi.nlm.nih.gov/pubmed/30962766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0784-3
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