LncRNA BCAR4, targeting to miR-665/STAT3 signaling, maintains cancer stem cells stemness and promotes tumorigenicity in colorectal cancer

BACKGROUND: Breast cancer anti-estrogen resistance 4 (BCAR4) is closely associated with colorectal cancer (CRC) initiation and propagation. However, the mechanisms underlying BCAR4 function in colon cancer remains largely unknown. In this study, we hypothesized that BCAR4 could regulate colon cancer...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Ouyang, Shurui, Zhou, Xin, Chen, Zhengquan, Wang, Maijian, Zheng, Xinbin, Xie, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438025/
https://ncbi.nlm.nih.gov/pubmed/30962766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0784-3
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