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LncRNA BCAR4, targeting to miR-665/STAT3 signaling, maintains cancer stem cells stemness and promotes tumorigenicity in colorectal cancer

BACKGROUND: Breast cancer anti-estrogen resistance 4 (BCAR4) is closely associated with colorectal cancer (CRC) initiation and propagation. However, the mechanisms underlying BCAR4 function in colon cancer remains largely unknown. In this study, we hypothesized that BCAR4 could regulate colon cancer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Ouyang, Shurui, Zhou, Xin, Chen, Zhengquan, Wang, Maijian, Zheng, Xinbin, Xie, Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438025/
https://ncbi.nlm.nih.gov/pubmed/30962766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0784-3
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