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Recent progress and challenges in screening and characterization of UGT1A1 inhibitors
Uridine-diphosphate glucuronosyltransferase 1A1 (UGT1A1) is an important conjugative enzyme in mammals that is responsible for the conjugation and detoxification of both endogenous and xenobiotic compounds. Strong inhibition of UGT1A1 may trigger adverse drug/herb–drug interactions, or result in met...
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| Publicado no: | Acta Pharm Sin B |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437557/ https://ncbi.nlm.nih.gov/pubmed/30972276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.09.005 |
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