ロード中...

DSM265 at 400 Milligrams Clears Asexual Stage Parasites but Not Mature Gametocytes from the Blood of Healthy Subjects Experimentally Infected with Plasmodium falciparum

DSM265 is a novel antimalarial drug in clinical development that acts as a selective inhibitor of Plasmodium dihydroorotate dehydrogenase. In a previous phase 1b study, a single 150-mg dose of DSM265 showed partial efficacy against experimentally induced blood-stage Plasmodium falciparum malaria (IB...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Collins, Katharine A., Rückle, Thomas, Elliott, Suzanne, Marquart, Louise, Ballard, Emma, Chalon, Stephan, Griffin, Paul, Möhrle, Jörg J., McCarthy, James S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437518/
https://ncbi.nlm.nih.gov/pubmed/30858218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01837-18
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!