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Modulation of the p75 neurotrophin receptor suppresses age-related basal forebrain cholinergic neuron degeneration
Age-related degeneration of basal forebrain cholinergic neurons (BFCNs) is linked to cognitive impairment. The p75 neurotrophin receptor (p75(NTR)) has been proposed to mediate neuronal degeneration in aging. Therefore, we tested the hypothesis that modifying p75(NTR) function would prevent or rever...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437186/ https://ncbi.nlm.nih.gov/pubmed/30918278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41654-8 |
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