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Low-Affinity Neurotrophin Receptor p75 Promotes the Transduction of Targeted Lentiviral Vectors to Cholinergic Neurons of Rat Basal Forebrain

Basal forebrain cholinergic neurons (BFCNs) are one of the most affected neuronal types in Alzheimer’s disease (AD), with their extensive loss documented at late stages of the pathology. While discriminatory provision of neuroprotective agents and trophic factors to these cells is thought to be of s...

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Bibliographic Details
Published in:Neurotherapeutics
Main Authors: Antyborzec, Inga, O’Leary, Valerie B., Dolly, James O., Ovsepian, Saak V.
Format: Artigo
Language:Inglês
Published: Springer US 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081123/
https://ncbi.nlm.nih.gov/pubmed/27220617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-016-0445-3
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