BCG Vaccination Prevents Reactivation of Latent Lymphatic Murine Tuberculosis Independently of CD4(+) T Cells

Tuberculosis (TB) is a major global public health problem causing significant mortality and morbidity. In addition to ~10.4 million cases of active TB annually, it is estimated that about two billion people are latently infected with Mycobacterium tuberculosis (Mtb), the causative agent of TB. React...

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Опубликовано в: :Front Immunol
Главные авторы: Sathkumara, Harindra D., Pai, Saparna, Aceves-Sánchez, Michel de Jesús, Ketheesan, Natkunam, Flores-Valdez, Mario Alberto, Kupz, Andreas
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437071/
https://ncbi.nlm.nih.gov/pubmed/30949177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00532
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