Mucosal delivery of ESX-1–expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes

Tuberculosis (TB) claims 1.5 million lives per year. This situation is largely due to the low efficacy of the only licensed TB vaccine, Bacillus Calmette–Guérin (BCG) against pulmonary TB. The metabolic disease type 2 diabetes (T2D) is a risk factor for TB and the mechanisms underlying increased TB...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Sathkumara, Harindra D., Muruganandah, Visai, Cooper, Martha M., Field, Matt A., Alim, Md Abdul, Brosch, Roland, Ketheesan, Natkunam, Govan, Brenda, Rush, Catherine M., Henning, Lars, Kupz, Andreas
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2020
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456134/
https://ncbi.nlm.nih.gov/pubmed/32778586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003235117
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla