Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

Understanding the tumor immune microenvironment (TIME) promises to be key for optimal cancer therapy, especially in triple-negative breast cancer (TNBC). Integrating spatial resolution of immune cells with laser capture microdissection gene expression profiles, we defined distinct TIME stratificatio...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Gruosso, Tina, Gigoux, Mathieu, Manem, Venkata Satya Kumar, Bertos, Nicholas, Zuo, Dongmei, Perlitch, Irina, Saleh, Sadiq Mehdi Ismail, Zhao, Hong, Souleimanova, Margarita, Johnson, Radia Marie, Monette, Anne, Ramos, Valentina Muñoz, Hallett, Michael Trevor, Stagg, John, Lapointe, Réjean, Omeroglu, Atilla, Meterissian, Sarkis, Buisseret, Laurence, Van den Eynden, Gert, Salgado, Roberto, Guiot, Marie-Christine, Haibe-Kains, Benjamin, Park, Morag
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436884/
https://ncbi.nlm.nih.gov/pubmed/30753167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96313
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