Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis

Cytomegalovirus (CMV) has been implicated in glioblastoma (GBM); however, a mechanistic connection in vivo has not been established. The purpose of this study is to characterize the effects of murine CMV (MCMV) on GBM growth in murine models. Syngeneic GBM models were established in mice perinatally...

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Pubblicato in:J Clin Invest
Autori principali: Krenzlin, Harald, Behera, Prajna, Lorenz, Viola, Passaro, Carmela, Zdioruk, Mykola, Nowicki, Michal O., Grauwet, Korneel, Zhang, Hong, Skubal, Magdalena, Ito, Hirotaka, Zane, Rachel, Gutknecht, Michael, Griessl, Marion B., Ricklefs, Franz, Ding, Lai, Peled, Sharon, Rooj, Arun, James, C. David, Cobbs, Charles S., Cook, Charles H., Chiocca, E. Antonio, Lawler, Sean E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436878/
https://ncbi.nlm.nih.gov/pubmed/30855281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123375
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