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CSIG-19. CYTOMEGALOVIRUS INFECTION LEADS TO NF-kB DEPENDENT UPREGULATION OF c-MET AND MGMT IN GLIOBLASTOMA AND RESISTANCE TO TEMOZOLOMIDE IN VIVO

INTRODUCTION: Cytomegalovirus (CMV), a member of the betaherpesvirinae subfamily widespread in human populations has been reported to be detectable in glioblastoma (GBM). We have recently shown that CMV latent infection promotes GBM growth in a mouse model. The mechanisms involved are not well-defin...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zdioruk, Mykola, Krenzlin, Harald, Oskar Nowicki, M, Cook, Charles H, Chiocca, Ennio, Lawler, Sean
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847473/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.189
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