A facile synthesis of a complex type N-glycan thiazoline as an effective inhibitor against the antibody-deactivating endo-β-N-acetylglucosaminidases

Endo-β-N-acetylglucosaminidases are a class of endoglycosidases that deglycosylate N-glycans from glycoproteins. We describe here a facile synthesis of a complex type N-glycan thiazoline as a new mechanism-based inhibitor for this class of enzymes. The synthesis started with the readily available si...

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Veröffentlicht in:J Carbohydr Chem
Hauptverfasser: Li, Chao, Zhu, Shilei, Tong, Xin, Ou, Chong, Wang, Lai-Xi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436815/
https://ncbi.nlm.nih.gov/pubmed/30930529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07328303.2017.1403616
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