Loss of function mutations in essential genes cause embryonic lethality in pigs

Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild populations, those alleles might be exposed by inbreeding, caused by matings between related parents that inherited the same recessive lethal alle...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Derks, Martijn F. L., Gjuvsland, Arne B., Bosse, Mirte, Lopes, Marcos S., van Son, Maren, Harlizius, Barbara, Tan, Beatrice F., Hamland, Hanne, Grindflek, Eli, Groenen, Martien A. M., Megens, Hendrik-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436757/
https://ncbi.nlm.nih.gov/pubmed/30875370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008055
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