Loss of function mutations in essential genes cause embryonic lethality in pigs

Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild populations, those alleles might be exposed by inbreeding, caused by matings between related parents that inherited the same recessive lethal alle...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Derks, Martijn F. L., Gjuvsland, Arne B., Bosse, Mirte, Lopes, Marcos S., van Son, Maren, Harlizius, Barbara, Tan, Beatrice F., Hamland, Hanne, Grindflek, Eli, Groenen, Martien A. M., Megens, Hendrik-Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436757/
https://ncbi.nlm.nih.gov/pubmed/30875370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008055
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