Loss of function mutations in essential genes cause embryonic lethality in pigs

Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild populations, those alleles might be exposed by inbreeding, caused by matings between related parents that inherited the same recessive lethal alle...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Derks, Martijn F. L., Gjuvsland, Arne B., Bosse, Mirte, Lopes, Marcos S., van Son, Maren, Harlizius, Barbara, Tan, Beatrice F., Hamland, Hanne, Grindflek, Eli, Groenen, Martien A. M., Megens, Hendrik-Jan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436757/
https://ncbi.nlm.nih.gov/pubmed/30875370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008055
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