Loss of function mutations in essential genes cause embryonic lethality in pigs

Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild populations, those alleles might be exposed by inbreeding, caused by matings between related parents that inherited the same recessive lethal alle...

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Publicat a:PLoS Genet
Autors principals: Derks, Martijn F. L., Gjuvsland, Arne B., Bosse, Mirte, Lopes, Marcos S., van Son, Maren, Harlizius, Barbara, Tan, Beatrice F., Hamland, Hanne, Grindflek, Eli, Groenen, Martien A. M., Megens, Hendrik-Jan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436757/
https://ncbi.nlm.nih.gov/pubmed/30875370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008055
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