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Loss of function mutations in essential genes cause embryonic lethality in pigs
Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild populations, those alleles might be exposed by inbreeding, caused by matings between related parents that inherited the same recessive lethal alle...
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| Pubblicato in: | PLoS Genet |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6436757/ https://ncbi.nlm.nih.gov/pubmed/30875370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008055 |
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