Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome

Livestock populations can be used to study recessive defects caused by deleterious alleles. The frequency of deleterious alleles including recessive lethal alleles can stay at high or moderate frequency within a population, especially if recessive lethal alleles exhibit an advantage for favourable t...

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Publicado en:PLoS Genet
Autores principales: Derks, Martijn F. L., Lopes, Marcos S., Bosse, Mirte, Madsen, Ole, Dibbits, Bert, Harlizius, Barbara, Groenen, Martien A. M., Megens, Hendrik-Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166978/
https://ncbi.nlm.nih.gov/pubmed/30231021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007661
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