Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome

Livestock populations can be used to study recessive defects caused by deleterious alleles. The frequency of deleterious alleles including recessive lethal alleles can stay at high or moderate frequency within a population, especially if recessive lethal alleles exhibit an advantage for favourable t...

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Udgivet i:PLoS Genet
Main Authors: Derks, Martijn F. L., Lopes, Marcos S., Bosse, Mirte, Madsen, Ole, Dibbits, Bert, Harlizius, Barbara, Groenen, Martien A. M., Megens, Hendrik-Jan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166978/
https://ncbi.nlm.nih.gov/pubmed/30231021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007661
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